Reply
cancel
Showing results for 
Search instead for 
Did you mean: 
Reply

Re: COVID-19 Vaccine

Highlighted
Community Guru
Bill H Member Since: Aug 18, 2017
1 of 20

There are multiple efforts underway to create a vaccine against the disease. This will address a recent effort by China to create a recombinant viral vaccine that is modified to produce antibodies to COVID-19 and drop them in the host, which will copy them and deeat COVID-19.

 

The chose mediated virus is adenovirus, which presents several major problems. First, the adenovirus is still infectious and causes illness on its own. This is fighting fire eith fire.Second, there are some fifty-odd , or more, adenoviruses. The most common ones act just like most rhinoiruses and corona viruses, causing respiratory infection. Not an improvement. Some adenoviruses cause conjunctivitis, others cause gastroenteritis, yet others cause very high fever. And, almost all of them target primarily young children. An adenovirus-mediated vaccine will cause us to broaden the number of vulnerable people, rarely a good idea.

 

We know a lot about corona viruses but very little about adenoviruses, which appear similar under a microscope. A vaccine was developed for the adenovirus and sold to the US military, which found the disease rampant among young men in their initial training. The vaccine has not been manufactured since 1994, and the last doses were shipped in 1996. Before infecting a population with another virus, I recommend we learn at least as much about the adenovirus as we know about corona viruses. That will take close to a decade. Then, COVID-19 is thought to be seasonal; Adenovirus is present year-round.

 

Recombinant viruses are agreed by virologists to be the most lethal for use in germ warfare. China will do what it wishes, and I haven't read their research results. Still, a combined COVID-19 and Adenovirus pandemic wouldn't be good news.

 

NEXT: How Vaccines Work

Highlighted
Ace Contributor
Zeeshan M Member Since: Apr 30, 2020
2 of 20

Bill H wrote:

 

NEXT: How Vaccines Work


Respectfully Bill... please, I BEG you: No!

 

I had to order a  paper of June issue from Journal of Molecular Biology  just to decipher your message.

____
Write like you're a death row inmate and the governor is out of the country and there's no chance for a pardon.
Highlighted
Community Guru
Bill H Member Since: Aug 18, 2017
3 of 20

Just for that, I'll write the next article in Esperanto, in which I have native fluency.

Highlighted
Community Guru
Bill H Member Since: Aug 18, 2017
4 of 20

Just for you, Zeesham:

 

Vakcinoj funkcias deĉenigante la imunosistemon por krei specialigitajn ĉelojn kiuj atakas la viruson, aŭ parton de la viruso, aŭ protektantaj la enirpunkton, kiun la viruso uzas por infekti individuajn ĉelojn. Iuj vakcinoj funkcias kontraŭ bakterioj. Vakcinoj foje inkluzivas malfortigitajn versiojn de la ĝermo, foje inkluzivas mortajn versiojn de la ĝermo (tiuj ofte postulas multoblajn dozojn, kiel kun polio), foje inkluzivas malfortigitajn versiojn de venenoj faritaj de la ĝermo, kaj foje inkluzivas parton de la ĝermo. La korpo lernas kiel fari la ĉelojn, kiuj atakas kaj venkas la ĝermojn.

 

English (the above is the Esperanto version)

 

Vaccines function by triggering the immune system to create specialized cells that attack the virus, or part of the virus, or that protect the point of entry the virus uses to infect individual cells. Some vaccines work against bacteria. Vaccines sometimes include weakened versions of the germ, sometimes include dead versions of the germ (these often require multiple doses, such as with polio), sometimes include weakened versions of poisons made by the germ, and sometimes include a part of the germ. The body learns how to make the cells that attack and defeat the germs.

Highlighted
Community Guru
Martina P Member Since: Jul 11, 2018
5 of 20

Zeeshan M wrote:

Bill H wrote:

 

NEXT: How Vaccines Work


Respectfully Bill... please, I BEG you: No!

 

I had to order a  paper of June issue from Journal of Molecular Biology  just to decipher your message.


It is hardly Bill's fault that you did not understand the text. And respectfully, beginning a sentence with "respectfully", does not make it such. 

Community Guru
Nichola L Member Since: Mar 13, 2015
6 of 20

 

 


Martina P wrote:

Zeeshan M wrote:

Bill H wrote:

 

NEXT: How Vaccines Work


Respectfully Bill... please, I BEG you: No!

 

I had to order a  paper of June issue from Journal of Molecular Biology  just to decipher your message.


It is hardly Bill's fault that you did not understand the text. And respectfully, beginning a sentence with "respectfully", does not make it such. 


_____________________________________________________________________

 

I didn't find that post disrespectful - just a plea not to ram further doom-and-gloom information down our throats when trying to come to terms with the pandemic has been bad enough.  

Highlighted
Community Guru
Bill H Member Since: Aug 18, 2017
7 of 20

The original post was prompted by  a lot of press coverage of China's work on a vaccine. Using a mediated virus is only one of many ways to create  vaccine; in this case, the virus used is itself a problem.

 

No intention for doom and gloom. The Chinese vaccine effort is worth pursuing, just not worth much hype or hope. There are other, much more promising, efforts underway in the Americas, Europe and Australia. I'm not following any work done in Asia, except for the Chinese work on a mediated-virus vaccine.

 

Rather than doom and gloom, I've been preaching a positive message since January. The virus is generally not dangerous to those under 65; we always had all the hospital and ICU beds, plus ventilators, we needed. We knew a lot about how to deal with the virus before the first case: encourage people to go outdoors, quarantine old people and those with chronic heart, lung and/or kidney conditions, and the immune-suppressed. Quarantine means strictly limiting outside contact with them. There are new treatments and vaccines under investigation; we're going to be fine.

Highlighted
Active Member
Seth V Member Since: Jun 22, 2020
8 of 20

Thank you for your work and your time, sir Smiley Wink

 

 

 

Highlighted
Community Guru
Petra R Member Since: Aug 3, 2011
9 of 20

Bill H wrote:

we always had all the hospital and ICU beds, plus ventilators, we needed. 


Please, Not this again.

"We" as in your little bubble and your local hospital or "we" as in "everywhere?"

I can assure you that there are a endless places all over the world, including in the USA, where there are and were not enough ICU beds or ventilators. That statement is easily verified as an absolute untruth.

 


Bill H wrote:

The virus is generally not dangerous to those under 65.


That is not what my doctor friends tell me. I mean real ones. You know, the type that is out there with an actual medical licence, treating real patients.

 

Just because it doesn't outright kill a high percentage of the "lower" risk groups doesn't mean it's not dangerous. The real damage done to those who haven't died from it remains to be seen, but already doctors (the real ones) are seeing cardiovascular issuess, neurological issues and more.  

 

Highlighted
Community Guru
Mary W Member Since: Nov 10, 2014
10 of 20

In my state, the average age of patients who require hospitalization is dropping.  In other words, more and more younger people are getting sicker.

TOP SOLUTION AUTHORS
TOP KUDOED MEMBERS